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TPH2 polyclonal antibody

货号: BS8744

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS8744

Product Name :TPH2 polyclonal antibody

Swiss-Prot :Q8IWU9

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:2000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :TPH2 polyclonal antibody detects endogenous levels of TPH2 protein.

BiowMW :~ 56kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Tryptophan 5-hydroxylase 2; Neuronal tryptophan hydroxylase; Tryptophan 5-monooxygenase 2; TPH2; NTPH

Immunogen :Recombinant full length Human TPH2.

Conjugate :Unconjugated

Modification :Unmodification

Immunofluorescence analysis of A549 cell using TPH2 antibody. Blue: DAPI for nuclear staining.

A circuit from lateral hypothalamic to dorsal hippocampal dentate gyrus modulates behavioral despair in mice

Journal10.1093/cercor/bhae399

ApplicationIF

IF2.9

SpeciesMouse

PMID39367727