Product Name :ZNF217 polyclonal antibody
Reactivity :Human,Mouse,Rat
Application_all :ELISA: 1:5000~1:10000
Background :ZNF217, also known as ZABC1, is a zinc finger protein belonging to the Krüppel C2H2-type zinc-finger protein family. It localizes to the nucleus and may play a role in transcriptional repression of a variety of genes through the recruitment of co-repressor complexes containing proteins such as CtBP, HDAC1 and HDAC2. In addition, ZNF217 participates in cell differentiation and appears to function as an oncogene. Expression of ZNF217 is amplified in various tumors and overexpression of the protein can attenuate apoptotic signals and lead to epithelial cell immortalization.
Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :ZNF217 polyclonal antibody detects endogenous levels of ZNF217 protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Zinc finger protein 217; ZNF217; ZABC1
Immunogen :KLH conjugated synthetic peptide derived from human ZNF217: 151-250/1061
Modification :Unmodification
