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SSX2 polyclonal antibody

货号: BS8632

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS8632

Product Name :SSX2 polyclonal antibody

Swiss-Prot :Q16385

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IF

Application_all :WB 1:500 - 1:2000 IF 1:50 - 1:200

Background :The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX1 and SSX4 family members, have been involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate, GeneID: 727837, located about 45 kb downstream in the opposite orientation on chromosome X.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :SSX2 polyclonal antibody detects endogenous levels of SSX2 protein.

BiowMW :Refer to figures

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Protein SSX2; Cancer/testis antigen 5.2; CT5.2; Synovial sarcoma, X breakpoint 2; Tumor antigen HOM-MEL-40; SSX2; Synonyms:SSX2A; SSX2B

Immunogen :Recombinant full length Human SSX2.

Conjugate :Unconjugated

Modification :Unmodification

Immunofluorescence analysis of HeLa cell using SSX2 antibody. Blue: DAPI for nuclear staining.