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FMO1 Polyclonal Antibody

货号: BS8574

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS8574

Product Name :FMO1 Polyclonal Antibody

Swiss-Prot :Q01740

Host :Rabbit

Reactivity :Human,Rat

Applications :WB IF/ICC

Application_all :WB: 1:500-1:1000 IF/ICC: 1:50-1:200

Background :Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Several transcript variants encoding different isoforms have been found for this gene.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :FMO1 Polyclonal Antibody detects endogenous levels of FMO1 protein.

BiowMW :~ 60 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :FMO1; flavin containing monooxygenase 1

Immunogen :A synthetic peptide corresponding to a sequence within amino acids 371-470 of human FMO1 (NP_002012.1).

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of lysates from Rat liver using FMO pAb at 1:1000 dilution.

Immunofluorescence analysis of paraffin-embedded Human liver tissue using FMO1 pAb at a dilution of 1:100 (40x lens).

免疫沉淀（IP）

免疫组织化学（IHC）