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PPAT polyclonal antibody

货号: BS8365

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS8365

Product Name :PPAT polyclonal antibody

Swiss-Prot :Q06203

Host :Rabbit

Reactivity :Human,Monkey

Applications :WB

Application_all :WB 1:500 - 1:2000

Background :Atase (amidophosphoribosyltransferase), also known as PPAT (phosphoribosyl pyrophosphate (PRPP) amidotransferase), PRAT or GPAT (glutamine phosphoribosyl pyrophosphate amidotransferase), is a ubiquitously expressed N-terminal nucleophile-type glutamine amidotransferase that belongs to the purine/pyrimidine phosphoribosyltransferase family. Existing as a homotetramer, Atase plays an important role in purine metabolism. More specifically, Atase functions as regulatory enzyme and contains one glutamine amidotransferase type-2 domain. Binding a magnesium ion and a 4Fe-4S cluster as cofactors, Atase catalyzes the first step (the rate-limiting step) in the purine nucleotide biosynthesis pathway, a two-step reaction that results in the formation of phosphoribosylamine from PRPP and glutamine. The first step of this reaction is catalyzed by the N-terminal glutaminase domain while the second step is catalyzed by the C-terminal PRTase domain.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :PPAT polyclonal antibody detects endogenous levels of PPAT protein.

BiowMW :~ 57 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Amidophosphoribosyltransferase ; Atase; Glutamine phosphoribosylpyrophosphate amidotransferase; GPAT; PPAT; GPAT

Immunogen :Recombinant full length Human PPAT.

Conjugate :Unconjugated

Modification :Unmodification

WesternBlot (WB) analysis of PPAT polyclonal antibody

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）