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GLP2R polyclonal antibody

货号: BS8286

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS8286

Product Name :GLP2R polyclonal antibody

Swiss-Prot :O95838

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB, IHC-P

Application_all :WB: 1:100-1:500 IHC-P: 1:50-1:200

Background :The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R).

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :GLP2R polyclonal antibody detects endogenous levels of GLP2R protein.

BiowMW :~ 67 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :GLP 2 R; GLP 2 receptor; GLP 2R; GLP-2 receptor; GLP-2-R; GLP-2R; GLP2 R; GLP2 Receptor; GLP2R; GLP2R_HUMAN; Glucagon Like Peptide 2 Receptor; Glucagon-like peptide 2 receptor

Immunogen :Recombinant fusion protein containing a sequence corresponding to amino acids 460-553 of human GLP2R (NP_004237.1).

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of extracts of various cell lines, using GLP2R antibody at 1:500 dilution.

Immunohistochemistry analysis of paraffin-embedded human colon using GLP2R Rabbit pAb at dilution of 1:20 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.