产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

LNX1 polyclonal antibody

货号: BS8252

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS8252

Product Name :LNX1 polyclonal antibody

Swiss-Prot :Q8TBB1

Host :Rabbit

Reactivity :Human

Applications :IF

Application_all :IF 1:50 - 1:100

Background :LNX1 (Ligand of Numb Protein X1, LNX, PDZ DOMAIN-CONTAINING RING FINGER PROTEIN 2, PDZRN2) is a RING finger and PDZ domain containing protein that associates with Numb, a phosphotyrosine-binding (PTB) domain-containing protein that functions as a cell fate determinant. Studies indicate that the protein contains an N-terminal PTB domain-binding motif and 4 PDZ domains. Northern blot analysis has detected the expression of LNX1 in heart, placenta, kindney, pancreas and brain tissues. By radiation hybrid mapping, the LNX gene was localized to human chromosome 4q12 between marker D4S1577 and marker D4S1594. Research suggests that the presence of multiple protein binding domains involved in signal transduction and association with Numb and SKIP may suggest an important role for LNX in tumorogenesis.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :LNX1 polyclonal antibody detects endogenous levels of LNX1 protein.

BiowMW :~ 81 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :E3 ubiquitin-protein ligase LNX; Ligand of Numb-protein X 1; Numb-binding protein 1; PDZ domain-containing RING finger protein 2; LNX1; LNX; PDZRN2; UNQ574/PRO1136

Immunogen :Recombinant full length Human LNX1.

Conjugate :Unconjugated

Modification :Unmodification

Immunofluorescence analysis of U2OS cell using LNX1 antibody. Blue: DAPI for nuclear staining.