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KIF2B polyclonal antibody

货号: BS8251

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS8251

Product Name :KIF2B polyclonal antibody

Swiss-Prot :Q8N4N8

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB 1:500 - 1:2000

Background :The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. KIF2B (kinesin family member 2B) is a 673 amino acid cytoplasmic protein that localizes to the kinetochore. Highly expressed in lung and ovary with moderate expression in heart, kidney, placenta skeletal muscle and spleen, KIF2B has microtubule depolymerization activity and is associated with peripheral translocation of lysosomes. Overexpression of KIF2B in cells result in abnormally large lysosome size and unusual positioning, which is some distance from their usual perinuclear location. KIF2B activity is critical for spindle assembly and chromosome movement.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :KIF2B polyclonal antibody detects endogenous levels of KIF2B protein.

BiowMW :~ 76 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Kinesin-like protein KIF2B; KIF2B

Immunogen :Recombinant full length Human KIF2B.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of various cell lines, using KIF2B antibody.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）