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RNGTT polyclonal antibody

货号: BS8211

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS8211

Product Name :RNGTT polyclonal antibody

Swiss-Prot :O60942

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IF

Application_all :WB: 1:500~1:2000 IF: 1:50~1:200

Background :RNGTT (RNA guanylyltransferase and 5'-phosphatase), also known as HCE, HCE1, hCAP or CAP1A, is a 597 amino acid protein that localizes to the nucleus and exists as four alternatively spliced isoforms. Expressed in kidney, lung, heart, brain, liver, testis, skin and muscle, RNGTT acts as a bifunctional mRNA-capping enzyme that exhibits RNA 5'-triphosphatase activity at its N-terminus and mRNA guanylyltransferase activity at its C-terminus. Via its catalytic activity, RNGTT facilitates the first two steps of mRNA cap formation, naming the removal of a γ-phosphate from the end of nascent mRNA and the subsequent transfer of the phospho residue to the 5’-diphosphate terminus. The gene encoding RNGTT maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :RNGTT polyclonal antibody detects endogenous levels of RNGTT protein.

BiowMW :~ 69 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :mRNA-capping enzyme; HCAP1; HCE; RNGTT; CAP1A

Immunogen :Recombinant full length Human RNGTT.

Conjugate :Unconjugated

Modification :Unmodification

WesternBlot (WB) analysis of RNGTT polyclonal antibody

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）