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TPD52L1 polyclonal antibody

货号: BS8203

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS8203

Product Name :TPD52L1 polyclonal antibody

Swiss-Prot :Q16890

Host :Rabbit

Reactivity :Human

Applications :IF

Application_all :IF 1:20 - 1:50

Background :The cell commits to dividing during the G2/M phase transition, and the timing of mitotic entry is tightly regulated to guarantee correct chromosome segregation. D53, also referred to as tumor protein D52-like 1 (TPD52L1), is a coiled-coil motif-bearing member of the D52 tumor protein family. D53 intereacts with 14-3-3, a negative regulator of the G2/M transition, in breast cancer cells. Expression of D53 is highly upregulated at the G2/M phase transition in breast cancer cell lines, and deregulated expression of this protein can adversely affect the completion of mitosis. D53 may function as a signaling intermediate and/or regulator of vesicle trafficking and cell proliferation.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :TPD52L1 polyclonal antibody detects endogenous levels of TPD52L1 protein.

BiowMW :~ 22 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Tumor protein D53; hD53; Tumor protein D52-like 1; TPD52L1

Immunogen :Recombinant full length Human TPD52L1.

Conjugate :Unconjugated

Modification :Unmodification

Immunofluorescence analysis of U2OS cell using TPD52L1 antibody. Blue: DAPI for nuclear staining.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）