产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

PNOC polyclonal antibody

货号: BS8183

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS8183

Product Name :PNOC polyclonal antibody

Swiss-Prot :Q13519

Host :Rabbit

Reactivity :Human

Applications :WB IF

Application_all :WB: 1:500~1:2000 IF: 1:50~1:200

Background :Nociception, a pain response mechanism, occurs in response to stimuli that threaten the integrity of an organism. The first synapses produced as a result of the initiation of nociception are modulated by excitatory amino acids (glutamate and aspartate) and many peptides (substance P, CGRP, CCK, endogenous opioids). Nociceptin (also designated orphanin FQ) is a neuronal peptide that is similar to opioid peptides. Nociceptin activates KOR-3 (kappa-type opioid receptor, also designated ORL1), a G protein-coupled receptor. Although similar to dynorphin A, a kappa opioid peptide, nociceptin functions to make animals hyperreactive to nociceptive stimulations. Nociceptin is also involved in locomotor behavior and may be involved in the modulation of synaptic plasticity in learning and memory.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :PNOC polyclonal antibody detects endogenous levels of PNOC protein.

BiowMW :~ 20 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Prepronociceptin; PNOC; OFQ

Immunogen :Recombinant full length Human PNOC.

Conjugate :Unconjugated

Modification :Unmodification

Immunofluorescence analysis of U2OS cell using PNOC antibody. Blue: DAPI for nuclear staining.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）