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CIAPIN1 polyclonal antibody

货号: BS8142

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS8142

Product Name :CIAPIN1 polyclonal antibody

Swiss-Prot :Q6FI81

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB,IHC,IF

Application_all :WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Background :The name of the protein Anamorsin, also designated cytokine-induced apoptosis inhibitor 1 (CIAPIN1), comes from the Latin term “ana-mors-in”, meaning “anti-death molecule”. During hematopoiesis, Anamorsin is crucial for mediating the anti-apoptotic effects of various cytokines. It is a ubiquitously expressed protein, and when it is overexpressed, it confers apoptotic resistance. Anamorsin is primarily expressed in the cytoplasm of liver, pancreas and heart tissue cells and does not show any homology to known apoptosis regulatory molecules of the Bcl-2 or CASP families, or to signal transduction molecules. Anamorsin expression in mouse cells confers resistance to apoptosis caused by IL-3 (interleukin-3) deprivation. Studies demonstrate that the addition of growth factors, such as EPO (erythropoietin), SCF (stem cell factor), TPO (thrombopoietin) or IL-3, all of which depend on RAS signaling, induce dose-dependent expression of Anamorsin in mouse cells.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CIAPIN1 polyclonal antibody detects endogenous levels of CIAPIN1 protein.

BiowMW :~ 39 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Anamorsin; Cytokine-induced apoptosis inhibitor 1; Fe-S cluster assembly protein DRE2 homolog; CIAPIN1; CUA001; PRO0915

Immunogen :Recombinant full length Human CIAPIN1.

Conjugate :Unconjugated

Modification :Unmodification

WesternBlot (WB) analysis of CIAPIN1 polyclonal antibody

Immunohistochemistry of paraffin-embedded human liver injury using CIAPIN1 Antibody.

Immunoprecipitation analysis of 200ug extracts of 293T cells, using 3 ug CIAPIN1 antibody.

免疫沉淀（IP）