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Osteocalcin polyclonal antibody

货号: BS7961

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS7961

Product Name :Osteocalcin polyclonal antibody

Swiss-Prot :P02818

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IF/ICC

Application_all :WB: 1:500~1:2000 IF/ICC: 1:50~1:200

Background :This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Osteocalcin polyclonal antibody detects endogenous levels of Osteocalcin protein.

BiowMW :~ 12 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :BGLAP; BGP; OC ; OCN; osteocalcin

Immunogen :A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Osteocalcin (BGLAP) (NP_954642.1).

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of U-87MG cells, using Osteocalcin antibody at 1:1000 dilution.

Western blot analysis of extracts of Rat lung, using Osteocalcin antibody at 1:1000 dilution.

Immunofluorescence analysis of MG-63 cells using Osteocalcin pAb at dilution of 1:200 (40x lens).

Immunofluorescence analysis of NIH/3T3 cells using Osteocalcin pAb at dilution of 1:200 (40x lens).

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JournalJournal Of Biomedical Materials Research Part A

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IF4.396

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COMP-Ang1 prevents periodontitic damages and enhances mandible bone growth in an experimental animal model

JournalBone

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IF4.147

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Local delivery of recombinant human FGF7 enhances bone formation in rat mandible defects

JournalJournal Of Bone And Mineral Metabolism

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IF2.297

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PMID27766421
Recombinant human IGF-1 produced by transgenic plant cell suspension culture enhances new bone formation in calvarial defects

JournalGrowth Hormone & Igf Research

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IF1.618

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Oral supplementation with p-coumaric acid protects mice against diabetes-associated spontaneous destruction of periodontal tissue

JournalJournal Of Periodontal Research

ApplicationIHC

IF4.419

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PMID31328274