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Acetyl-DNMT1-K1127/K1129/K1131/K1133 polyclonal antibody

货号: BS7948

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS7948

Product Name :Acetyl-DNMT1-K1127/K1129/K1131/K1133 polyclonal antibody

Swiss-Prot :P26358

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :IHC, IF/ICC

Application_all :IHC,1:50 - 1:100|IF/ICC,1:50 - 1:100

Background :This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Acetylated Antibodies

BiowMW :Refer to figures

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ADCADN;AIM;CXXC9;DNMT;HSN1E;MCMT;m.HsaI;DNMT1

Immunogen :A synthetic acetylated peptide around K1127 & K1129 & K1131 & K1133 of human DNMT1(NP_001124295.1).

Conjugate :Unconjugated

Modification :Acetylated

Immunofluorescence analysis of C6 cells using Acetyl-DNMT1-K1127/K1129/K1131/K1133 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）