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TTC11/FIS1 polyclonal antibody

货号: BS7881

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS7881

Product Name :TTC11/FIS1 polyclonal antibody

Swiss-Prot :Q9Y3D6

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IF/ICC, IP

Application_all :WB,1:500 - 1:2000|IF/ICC,1:50 - 1:200|IP,1:50 - 1:200

Background :The balance between fission and fusion regulates the morphology of mitochondria. TTC11 is a component of a mitochondrial complex that promotes mitochondrial fission (James et al., 2003 [PubMed 12783892]).[supplied by OMIM, Mar 2008]

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Polyclonal Antibodies

BiowMW :17KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CGI-135;TTC11;FIS1;TTC11 / FIS1;fission

Immunogen :Recombinant fusion protein of human TTC11/FIS1(NP_057152.2).

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of 293T cells, using TTC11/FIS1 Rabbit pAb at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 30s.

Confocal immunofluorescence analysis of HeLa cells using TTC11/FIS1 antibody at dilution of 1:50 . Blue: DAPI for nuclear staining.

GPRASP2 deficiency contributes to apoptosis in the spiral ganglion cells via the AMPK/DRP1 signaling pathway

JournalHeliyon

ApplicationWB

IF3.4

SpeciesMouse

PMID39253164