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UGT1A4 polyclonal antibody

货号: BS7614

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS7614

Product Name :UGT1A4 polyclonal antibody

Swiss-Prot :P22310

Host :Rabbit

Reactivity :Human

Applications :WB IHC-P

Application_all :WB 1:500 - 1:1000 IHC-P 1:50 - 1:100

Background :This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. This enzyme has some glucuronidase activity towards bilirubin, although is is more active on amines, steroids, and sapogenins.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :UGT1A4 polyclonal antibody detects endogenous levels of UGT1A4 protein.

BiowMW :~ 60 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :UGT1A4;HUG-BR2;UDPGT;UDPGT 1-4;UGT-1D;UGT1-04;UGT1.4;UGT1A4S;UGT1D;UDPGT1-4

Immunogen :Synthetic peptide of human UGT1A4.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of UGT1A4 in Human fetal intestines and Human liver cancer lysates using UGT1A4 antibody.

Immunohistochemistry analysis of paraffin-embedded Human brain using UGT1A4 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.