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DNMT1 polyclonal antibody

货号: BS7606

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS7606

Product Name :DNMT1 polyclonal antibody

Swiss-Prot :P26358

Host :Rabbit

Reactivity :Human

Applications :WB, IF/ICC, IP

Application_all :WB,1:500 - 1:2000|IF/ICC,1:50 - 1:200|IP,1:50 - 1:100

Background :This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Polyclonal Antibodies

BiowMW :200kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ADCADN;AIM;CXXC9;DNMT;HSN1E;MCMT;m.HsaI;DNMT1

Immunogen :Recombinant fusion protein of human DNMT1(NP_001370.1).

Conjugate :Unconjugated

Modification :Unmodification

Immunoprecipitation analysis of 200ug extracts of 293T cells using 3ug DNMT1 antibody . Western blot was performed from the immunoprecipitate using DNMT1 antibody at a dilution of 1:1000.

Intronic miR-140-5p contributes to beta-cypermethrin-mediated testosterone decline

JournalScience Of The Total Environment

ApplicationWB

IF7.963

SpeciesRat,Mouse

PMID34794910
Identification of Expression Patterns and Potential Prognostic Significance of m 5 C-Related Regulators in Head and Neck Squamous Cell Carcinoma

JournalFrontiers in Oncology

ApplicationIF

IF6.244

SpeciesHuman

PMID33912441