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NLK polyclonal antibody

货号: BS7516
价格 1140
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :BS7516
Product Name :NLK polyclonal antibody
Swiss-Prot :Q9UBE8
Host :Rabbit
Reactivity :Human,Mouse,Rat
Applications :WB IHC
Application_all :WB: 1:500~1:2000 IHC: 1:50~1:200
Background :The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated through two closely related MAP kinases, p44 and p42, designated extracellular-signal related kinase 1 (ERK 1) and ERK 2, respectively. ERK proteins are regulated by dual phosphorylation at specific tyrosine and threonine sites mapping within a characteristic Thr-Glu-Tyr motif. Phosphorylation at both Thr-183 and Tyr-185 is required for full enzymatic activation. In response to activation, MAP kinases phosphorylate downstream components on serine and threonine (5,6). Nlk, or nemo-like kinase, is a murine homolog of the Drosophila nemo (nmo) gene. Nlk and Nmo have sequence homology to both the ERK MAP kinases and the cyclin dependent kinases. Nlk is a nuclear protein with the ability to autophosphorylate.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :NLK polyclonal antibody detects endogenous levels of NLK protein.
BiowMW :~ 68 kDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :LAK1; Nemo like kinase; Nemo-like kinase; Nlk; NLK_HUMAN; Protein LAK1; Serine/threonine protein kinase NLK; Serine/threonine-protein kinase NLK;
Immunogen :Recombinant full length Human NLK.
Conjugate :Unconjugated
Modification :Unmodification
Western blot analysis of NLK polyclonal antibody
  • Declined miR-181a-5p expression is associated with impaired natural killer cell development and function with aging
    JournalAging Cell
    ApplicationWB
    IF9.304
    SpeciesMouse

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400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com