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NKX2-1 polyclonal antibody

货号: BS7492
价格 1140
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :BS7492
Product Name :NKX2-1 polyclonal antibody
Swiss-Prot :P43699
Host :Rabbit
Reactivity :Human, Rat
Applications :WB
Application_all :WB,1:500 - 1:2000
Background :This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription.
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Polyclonal Antibodies
BiowMW :39KDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :NKX2-1;BCH;BHC;NK-2;NKX2.1;NKX2A;NMTC1;T/EBP;TEBP;TITF1;TTF-1;TTF1
Immunogen :Recombinant fusion protein of human NKX2-1(NP_003308.1).
Conjugate :Unconjugated
Modification :Unmodification
Western blot analysis of extracts of NCI-H460 cells, using NKX2-1 antibody at 1:500 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 30s.

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400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com