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Phospho-GSK3β-Y216 + GSK3α-Y279 polyclonal antibody

货号: BS74004

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :BS74004

Product Name :Phospho-GSK3β-Y216 + GSK3α-Y279 polyclonal antibody

Swiss-Prot :P49841

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB,1:500 - 1:2000

Background :The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Phosphorylated Antibodies

BiowMW :50kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :GSK3B;gsk-3β

Immunogen :A synthetic phosphorylated peptide around Y216 of human GSK3β(NP_001139628).

Conjugate :Unconjugated

Modification :Phosphorylated

Western blot analysis of extracts of 293T cells, using Phospho-GSK3β-Y216 + GSK3α-Y279 antibody at 1:1000 dilution. 293T cells were treated by Insulin for 10 minutes or treated by 10% FBS for 30 minutes after serum-starvation overnight.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% BSA.