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OGT polyclonal antibody

货号: BS7343

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS7343

Product Name :OGT polyclonal antibody

Swiss-Prot :O15294

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:2000 IHC: 1:50~1:200

Background :This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :OGT polyclonal antibody detects endogenous levels of OGT protein.

BiowMW :~117 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :GlcNAc transferase; HRNT1; MGC22921; O GlcNAc; O GlcNAc transferase p110 subunit; O GlcNAc transferase subunit p110; O linked N acetylglucosamine (GlcNAc) transferase (UDP N acetylglucosamine:polypeptide N acetylglucosaminyl transferase); O linked N acetylglucosamine (GlcNAc) transferase; O linked N acetylglucosamine transferase 110 kDa subunit; O-GlcNAc transferase subunit p110; O-linked N-acetylglucosamine transferase 110 kDa subunit; OGT; OGT1_HUMAN; UDP N acetylglucosamine peptide N acetylglucosaminyltransferase 110 kDa subunit; UDP N acetylglucosamine peptide N acetylglucosaminyltransferase GlcNAc transferase; UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit; UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase; Uridinediphospho N acetylglucosamine:polypeptide beta N acetylglucosaminyl transferase;

Immunogen :Recombinant full length Human OGT.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of OGT polyclonal antibody

Immunohistochemistry (IHC) analysis of OGT polyclonal antibody in paraffin-embedded Human Breast Cancer tissue.

Immunofluorescence analysis of U2OS cells, using OGT polyclonal antibody

Pyridostigmine regulates glucose metabolism and mitochondrial homeostasis to reduce myocardial vulnerability to injury in diabetic mice

JournalAmerican Journal Of Physiology-Endocrinology And Metabolism

ApplicationWB

IF4.125

SpeciesMouse

PMID31211620
Suppressed OGT expression inhibits cell proliferation while inducing cell apoptosis in bladder cancer

JournalBmc Cancer

ApplicationIHC,WB

IF3.15

SpeciesHuman

PMID30453909