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GRIN2B polyclonal antibody

货号: BS72928

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS72928

Product Name :GRIN2B polyclonal antibody

Swiss-Prot :Q13224

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IF/ICC

Application_all :WB,1:500 - 1:2000|IF/ICC,1:50 - 1:200

Background :N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Polyclonal Antibodies

BiowMW :166KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :GRIN2B;EIEE27;GluN2B;MRD6;NMDAR2B;NR2B;hNR3

Immunogen :Recombinant fusion protein of human GRIN2B(NP_000825.2).

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of various cell lines, using GRIN2B antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 1s.

Immunofluorescence analysis of Neuro-2a cells using GRIN2B Rabbit pAb at dilution of 1:100 . Blue: DAPI for nuclear staining.

Immunofluorescence analysis of SH-SY5Y cells using GRIN2B Rabbit pAb at dilution of 1:100 . Blue: DAPI for nuclear staining.

Inhibition of the integrated stress response reverses oxidative stress damage-induced postoperative cognitive dysfunction.

JournalFrontiers in Cellular Neuroscience

ApplicationWB

IF6.147

SpeciesMouse

PMID36212697
Protein phosphatase 2A deficiency in hippocampal CA1 inhibits priming effect of morphine on conditioned place preference in mice

JournalCEREBRAL CORTEX

ApplicationWB

IF4.861

SpeciesMouse

PMID36627245