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OLR1 polyclonal antibody

货号: BS7287

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS7287

Product Name :OLR1 polyclonal antibody

Swiss-Prot :P78380

Host :Rabbit

Reactivity :Human,Rabbit,Rat

Applications :WB IHC ICC IF

Application_all :WB=1:500-2000 IHC=1:100-500 ICC=1:100-500 IF=1:100-500

Background :This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :OLR1 polyclonal antibody detects endogenous levels of OLR1 protein.

BiowMW :~ 50 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Lectin-type oxidized LDL receptor 1; OLR1; lectin-like low density lipoprotein receptor-1; Oxidized low-density lipoprotein receptor 1; Ox-LDL receptor 1; Lectin-like oxidized LDL receptor 1; Lectin-like oxLDL receptor 1; LOX-1; BLOX1; Contains: Oxidized low-density lipoprotein receptor 1, soluble form A; Oxidized low-density lipoprotein receptor 1, soluble form B; OLR1_HUMAN.

Immunogen :KLH conjugated synthetic peptide derived from rabbit LOX-1:201-273/273 <Extracellular>

Conjugate :Unconjugated

Modification :Unmodification

Sample: Cerebrum (Rat) Lysate at 40 ug Primary: Anti- LOX1 at 1/300 dilution

Sample:293T(Human) Cell Lysate at 30 ug Primary: Anti-LOX 1 at 1/300 dilution

Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (LOX 1) Polyclonal Antibody, Unconjugated at 1:500 overnight at 4℃.

Paraformaldehyde-fixed, paraffin embedded (Rabbit brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (LOX 1) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4℃。