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LDLR polyclonal antibody

货号: BS72690
价格 1140
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :BS72690
Product Name :LDLR polyclonal antibody
Swiss-Prot :P01130
Host :Rabbit
Reactivity :Human,Mouse
Applications :WB,IHC,IF
Application_all :WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Background :The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :LDLR polyclonal antibody detects endogenous levels of LDLR protein.
BiowMW :120kDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :FH;FHC;LDLCQ2
Immunogen :A synthetic peptide of human LDLR
Conjugate :Unconjugated
Modification :Unmodification
Western blot analysis of extracts of various cell lines, using LDLR antibody.

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400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com