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LEF1 polyclonal antibody

货号: BS72309

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS72309

Product Name :LEF1 polyclonal antibody

Swiss-Prot :Q9UJU2

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB ELISA

Application_all :WB 1:500 - 1:2000 ELISA 1:5000 - 1:10000

Background :This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :LEF1 polyclonal antibody detects endogenous levels of LEF1 protein.

BiowMW :~ 47 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Wntβ catenin signaling，Contribution of ECM and Cytoskeletal Factors to EMT,

Alternative Name :LEF-1; TCF10; TCF1ALPHA; TCF7L3

Immunogen :KLH conjugated synthetic peptide derived from human LEF-1: 331-399/399

Conjugate :Unconjugated

Modification :Unmodification

Sample: Lymph nodes (Mouse) Lysate at 30 ug Primary: Anti- LEF-1 at 1/300 dilution

免疫沉淀（IP）

免疫组织化学（IHC）