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NRF-1 polyclonal antibody

货号: BS7179
价格 1140
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :BS7179
Product Name :NRF-1 polyclonal antibody
Swiss-Prot :Q16656
Host :Rabbit
Reactivity :Human,Mouse,Rat
Applications :WB IF/ICC
Application_all :WB,1:500 - 1:2000|IF/ICC,1:50 - 1:200
Background :Nuclear respiratory factor-1 (NRF-1) is a transcriptional activator that has been implicated in the nuclear control of respiratory chain expression in mammalian cells. The NRF-1 gene is expressed during oogenesis and during the early stages of embryogenesis. In vitro studies have implicated NRF-1 in the transcriptional expression of nuclear genes required for mitochondrial respiratory function, as well as for other fundamental cellular activities. While most isolated wild-type and NRF-1+/- blastocysts continue to develop normally in vitro, NRF-1-/- blastocysts lack this ability, despite their normal morphology. NRF-1 is specifically required in the maintenance of mtDNA and respiratory chain function during early embryogenesis. NRF-1 also plays a key role in cellular adaptation to energy demands by translating physiological signals into an increased capacity for generating energy.
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :NRF-1 polyclonal antibody detects endogenous levels of NRF-1 protein.
BiowMW :~ 70 kDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Nuclear respiratory factor 1, NRF-1, Alpha palindromic-binding protein, Alpha-pal, NRF1
Immunogen :Recombinant full length Human NRF-1.
Conjugate :Unconjugated
Modification :Unmodified
Western blot analysis of NRF1 expression in MCF7 (A), mouse testis (B) whole cell lysates.
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400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com