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CDK2AP1 polyclonal antibody

货号: BS71724

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS71724

Product Name :CDK2AP1 polyclonal antibody

Swiss-Prot :O14519

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB 1:200 - 1:1000

Background :The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CDK2AP1 polyclonal antibody detects endogenous levels of CDK2AP1 protein.

BiowMW :~ 13 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :DOC1; ST19; DORC1; doc-1; p12DOC-1;

Immunogen :A synthetic peptide of human CDK2AP1

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of CDK2AP1 antibody.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）