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SLC22A12 polyclonal antibody

货号: BS71631

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS71631

Product Name :SLC22A12 polyclonal antibody

Swiss-Prot :Q96S37

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:100~1:500

Background :The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :SLC22A12 polyclonal antibody detects endogenous levels of SLC22A12 protein.

BiowMW :~ 60 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :RST; UAT; OAT4L; URAT1; hURAT1

Immunogen :Recombinant fusion protein containing a sequence corresponding to amino acids 30-150 of human SLC22A12 (NP_653186.2).

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Mouse kidney, using SLC22A12 antibody at 1:400 dilution.

Phyllanthi Fructus ameliorates hyperuricemia and kidney injure via inhibiting uric acid synthesis, modulating urate transporters, and alleviating inflammation

Journal10.1038/s41598-024-79350-x

ApplicationWB

IF3.8

SpeciesRat

PMID39528682