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LIMK2 polyclonal antibody

货号: BS7151

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS7151

Product Name :LIMK2 polyclonal antibody

Swiss-Prot :P53671

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB,IF

Application_all :WB 1:500 - 1:2000 IF 1:50 - 1:200

Background :Proteins containing LIM motifs are typically involved in cell fate determination and growth control. A family of proteins designated LIM kinases, incuding LIMK-1 and LIMK-2, has been identified. LIMK-1 has been shown to regulate the stabilization of F-Actin structures and Cofilin activity, indicating that LIMK-1 plays a role in a signaling pathway involved in the regulation of cell motility and morpho-genesis. LIMK-1 inhibits neuronal differentiation of PC12 cells, and it is thought to act by interfering with events downstream of MAPK activation. Expression patterns of LIMK-1 and LIMK-2 suggest that these proteins may have different functions during development. A truncated form of LIMK-2 has been identified in adult testis that is thought to arise from an alternative initiation exon.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :LIMK2 polyclonal antibody detects endogenous levels of LIMK2 protein.

BiowMW :~ 80 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Regulation of Microtubule Dynamics,

Alternative Name :LIM domain kinase 2; LIMK 2; LIMK2

Immunogen :Recombinant full length Human LIMK2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of LIMK2 polyclonal antibody

免疫沉淀（IP）

免疫组织化学（IHC）