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IL18R1/IL-18 R alpha polyclonal antibody

货号: BS7143
价格 1140
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :BS7143
Product Name :IL18R1/IL-18 R alpha polyclonal antibody
Swiss-Prot :Q13478
Host :Rabbit
Reactivity :Human, Mouse, Rat
Applications :WB, IHC, IF/ICC
Application_all :WB,1:500 - 1:1000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200
Background :The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Polyclonal Antibodies
BiowMW :75kDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :IL18R1;CD218a;CDw218a;IL-1Rrp;IL18RA;IL1RRP
Immunogen :Recombinant fusion protein of human IL18R1/IL-18 R alpha(NP_003846.1).
Conjugate :Unconjugated
Modification :Unmodification
Western blot analysis of extracts of NCI-H460 cells, using IL18R1/IL-18 R alpha antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 90s.
Immunohistochemistry of paraffin-embedded human colon carcinoma using IL18R1/IL-18 R alpha Rabbit pAb at dilution of 1:150 .Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Immunohistochemistry of paraffin-embedded human lung cancer using IL18R1/IL-18 R alpha Rabbit pAb at dilution of 1:150 .Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
  • Ketogenic diet ameliorates inflammation by inhibiting the NLRP3 inflammasome in osteoarthritis
    JournalARTHRITIS RESEARCH & THERAPY
    ApplicationIHC
    IF5.156
    SpeciesRat

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400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com