产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

Mfn2 polyclonal antibody

货号: BS71425

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS71425

Product Name :Mfn2 polyclonal antibody

Swiss-Prot :O95140

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:2000 IHC: 1:50~1:200

Background :This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mfn2 polyclonal antibody detects endogenous levels of Mfn2 protein.

BiowMW :~ 86 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :HSG; MARF; CMT2A; CPRP1; CMT2A2;

Immunogen :Recombinant protein of human MFN2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of various cells, using MFN2 antibody.

Mitofusion-2-mediated alleviation of insulin resistance in rats through reduction in lipid intermediate accumulation in skeletal muscle

JournalJournal Of Biomedical Science

ApplicationWB

IF5.762

SpeciesRat

PMID
Overexpression of mitofusin 2 improves translocation of glucose transporter 4 in skeletal muscle of high‑fat diet‑fed rats through AMP‑activated protein kinase signaling

JournalMolecular Medicine Reports

ApplicationWB

IF2.952

SpeciesRat

PMID
Mitofusin 2 deficiency leads to oxidative stress that contributes to insulin resistance in rat skeletal muscle cells

JournalMolecular Biology Reports

ApplicationWB

IF2.107

SpeciesRat

PMID25034891
Comparative proteomics reveals that lipid droplet-anchored mitochondria are more sensitive to cold in brown adipocytes

JournalBiochimica Et Biophysica Acta-Molecular And Cell Biology Of Lipids

ApplicationWB

IF4.698

SpeciesMouse

PMID34147658
YiQiFuMai Powder Injection Attenuates Coronary Artery Ligation-Induced Heart Failure Through Improving Mitochondrial Function via Regulating ROS Generation and CaMKII Signaling Pathways

JournalFrontiers in Pharmacology

ApplicationWB

IF4.225

SpeciesRat

PMID31031629