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PDE3B polyclonal antibody

货号: BS71236

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS71236

Product Name :PDE3B polyclonal antibody

Swiss-Prot :Q13370

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB

Application_all :WB,1:500 - 1:2000

Background :Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Polyclonal Antibodies

BiowMW :115kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PDE3B;HcGIP1;cGIPDE1

Immunogen :Recombinant fusion protein of human PDE3B(NP_000913.2).

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of various cell lines, using PDE3B antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 40s.

Omega-3 polyunsaturated fatty acids ameliorate ethanol-induced adipose hyperlipolysis: A mechanism for hepatoprotective effect against alcoholic liver disease

JournalBiochimica Et Biophysica Acta-Molecular Basis Of Disease

ApplicationWB

IF4.352

SpeciesMouse

PMID
Inhibition of lipolysis by ilexgenin A via AMPK activation contributes to the prevention of hepatic insulin resistance

JournalEuropean Journal Of Pharmacology

ApplicationWB

IF3.263

SpeciesMouse

PMID28739087
Mangiferin protects against alcoholic liver injury via suppression of inflammation-induced adipose hyperlipolysis

JournalFood & Function

ApplicationWB

IF4.171

SpeciesMouse

PMID32969440
Astragaloside IV Inhibits Adipose Lipolysis and Reduces Hepatic Glucose Production via Akt Dependent PDE3B Expression in HFD-Fed Mice

JournalFrontiers in Physiology

ApplicationWB,IF

IF3.201

SpeciesMouse

PMID29410630