产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

CTSC polyclonal antibody

货号: BS71208

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS71208

Product Name :CTSC polyclonal antibody

Swiss-Prot :P53634

Host :Rabbit

Reactivity :Mouse

Applications :IF/ICC

Application_all :IF/ICC,1:50 - 1:200

Background :This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Polyclonal Antibodies

BiowMW :70kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CTSC;CPPI;DPP-I;DPP1;DPPI;HMS;JP;JPD;PALS;PDON1;PLS

Immunogen :Recombinant fusion protein of human CTSC(NP_001805.3).

Conjugate :Unconjugated

Modification :Unmodification

Immunofluorescence analysis of L929 using CTSC antibody at dilution of 1:100 . Blue: DAPI for nuclear staining.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）