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EPOR polyclonal antibody

货号: BS7113

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS7113

Product Name :EPOR polyclonal antibody

Swiss-Prot :P19235

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IF/ICC

Application_all :WB,1:500 - 1:2000|IF/ICC,1:50 - 1:200

Background :This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Polyclonal Antibodies

BiowMW :60KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :EPOR;EPO-R

Immunogen :A synthetic peptide of human EPOR(NP_000112.1).

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Mouse liver, using EPOR antibody at 1:1200 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 60s.

Immunofluorescence analysis of Mouse fetal using EPOR Rabbit pAb at dilution of 1:100. Blue: DAPI for nuclear staining.

KIAA0101 is associated with human renal cell carcinoma proliferation and migration induced by erythropoietin

JournalOncotarget

ApplicationWB

IF0

SpeciesHuman

PMID26575329
Chicoric Acid Improves Heart and Blood Responses to Hypobaric Hypoxia in Tibetan Yaks

JournalAmerican Journal Of Chinese Medicine

ApplicationWB

IF4.667

SpeciesBovine(Tibetan Yaks)

PMID29433395