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TRPC6 polyclonal antibody

货号: BS71105

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS71105

Product Name :TRPC6 polyclonal antibody

Swiss-Prot :Q9Y210

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC-P

Application_all :WB: 1:500-1:1000 IHC-P: 1:50-1:200

Background :The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :TRPC6 polyclonal antibody detects endogenous levels of TRPC6 protein.

BiowMW :~ 106 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TRP6; FSGS2

Immunogen :A synthetic peptide corresponding to a sequence within amino acids 500-600 of human TRPC6 (NP_004612.2).

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of extracts of Mouse pancreas, using TRPC6 antibody at 1:1000 dilution.

Western blot analysis of extracts of Rat brain, using TRPC6 antibody at 1:1000 dilution.

Immunohistochemistry analysis of paraffin-embedded human esophageal cancer using TRPC6 pAb at dilution of 1:100 (40x lens).

Immunohistochemistry analysis of paraffin-embedded mouse kidney using TRPC6 pAb at dilution of 1:100 (40x lens).

Piperlonguminine attenuates renal fibrosis by inhibiting TRPC6

JournalJOURNAL OF ETHNOPHARMACOLOGY

ApplicationWB

IF5.195

SpeciesMouse,Human

PMID37121453