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C5 polyclonal antibody

货号: BS71081

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS71081

Product Name :C5 polyclonal antibody

Swiss-Prot :P01031

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:200

Background :The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to a susceptibility to liver fibrosis and to rheumatoid arthritis.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :C5 polyclonal antibody detects endogenous levels of C5 protein.

BiowMW :~ 110 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Complement C5; CPAMD4

Immunogen :Recombinant protein of human C5.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extract of various cells, using C5 antibody.

Immunohistochemistry of paraffin-embedded human stomach using C5 antibody at dilution of 1:100 (40x lens).

免疫沉淀（IP）

免疫组织化学（IHC）