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NDUFV1 polyclonal antibody

货号: BS71051

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS71051

Product Name :NDUFV1 polyclonal antibody

Swiss-Prot :P49821

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IF IHC ELISA

Application_all :WB: 1:500~1:2000 IHC: 1:100~1:500 IF: 1:100~1:500 ELISA: 1:5000~1:10000

Background :The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :NDUFV1 polyclonal antibody detects endogenous levels of NDUFV1 protein.

BiowMW :~ 49 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :UQOR1; CI-51K; CI51KD

Immunogen :KLH conjugated synthetic peptide derived from human NDUFV1: 41-140/464

Conjugate :Unconjugated

Modification :Unmodification

Primary: Anti- NDUFV1 at 1/1000 dilution

Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (NDUFV1) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C.