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TNNI2 polyclonal antibody

货号: BS71003

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS71003

Product Name :TNNI2 polyclonal antibody

Swiss-Prot :P48788

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB 1:500 - 1:1000

Background :This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :TNNI2 polyclonal antibody detects endogenous levels of TNNI2 protein.

BiowMW :~ 21 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :DA2B; FSSV; fsTnI; AMCD2B

Immunogen :Synthetic peptide, corresponding to Human TNNI2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of TNNI2 polyclonal antibody at 1:500 dilution LaneA:The skeletal muscle tissue lysate of Mouse(40ug) LaneB:The skeletal muscle tissue lysate of Rat(40ug)