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TRIAP1 polyclonal antibody

货号: BS70786

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS70786

Product Name :TRIAP1 polyclonal antibody

Swiss-Prot :O43715

Host :Rabbit

Reactivity :Human

Applications :WB IF

Application_all :WB 1:500 - 1:2000 IF 1:50 - 1:100

Background :Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane (PubMed:23931759). Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo) (PubMed:26071602). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis (PubMed:15735003)

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :TRIAP1 polyclonal antibody detects endogenous levels of TRIAP1 protein.

BiowMW :~ 9 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TP53-regulated inhibitor of apoptosis 1; Protein 15E1.1; WF-1; p53-inducible cell-survival factor; p53CSV; TRIAP1; 15E1.1; HSPC132

Immunogen :Recombinant protein of human TRIAP1.

Conjugate :Unconjugated

Modification :Unmodification

Immunofluorescence analysis of MCF7 cell using TRIAP1 antibody. Blue: DAPI for nuclear staining.