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SF3B3 polyclonal antibody

货号: BS70723

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS70723

Product Name :SF3B3 polyclonal antibody

Swiss-Prot :Q15393

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Background :This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :SF3B3 polyclonal antibody detects endogenous levels of SF3B3 protein.

BiowMW :~ 136 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :RSE1; SAP130; SF3b130; STAF130;

Immunogen :Recombinant protein of human SF3B3.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of mouse tissues, using SF3B3 antibody.

Immunohistochemistry of paraffin-embedded rat brain using SF3B3 antibody at dilution of 1:200 (40x lens).

Immunohistochemistry of paraffin-embedded rat kidney using SF3B3 antibody at dilution of 1:200 (40x lens).

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