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STAB2 polyclonal antibody

货号: BS70708

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS70708

Product Name :STAB2 polyclonal antibody

Swiss-Prot :Q8WWQ8

Host :Rabbit

Reactivity :Mouse

Applications :ELISA IHC ICC IF

Application_all :ELISA 1:5000-10000 IHC 1:100-500 ICC 1:100-500 IF 1:100-500

Background :This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes.

Product :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :STAB2 polyclonal antibody detects endogenous levels of STAB2 protein.

BiowMW :~ 154, 275 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :STAB 2; 190 kDa form stabilin-2; 190 kDa hyaluronan receptor for endocytosis; EGF-like; FAS1 EGF-like and X-link domain-containing adhesion molecule 2; Fasciclin; FEEL-2; FEEL2; FELL; FEX2; HARE; Hyaluronan receptor for endocytosis; laminin-type EGF-like and link domain-containing scavenger receptor 2; link domain-containing scavenger receptor 2; STAB-2; Stab2; STAB2_HUMAN.

Immunogen :KLH conjugated synthetic peptide derived from human Stabilin 2 :2201-2300/2551 <Extracellular>

Conjugate :Unconjugated

Modification :Unmodification

Tissue/cell: mouse spleen tissue;4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Blocking buffer at 37℃ for 20 min; Incubation: Anti-Stabilin 2 Polyclonal Antibody, Unconjugated 1:200, overnight at 4°C; The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37°C. DAPI was used to stain the cell nuclei.