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Cleaved-Spectrin α II (D1185) polyclonal antibody（KU）

货号: BS7056

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS7056

Product Name :Cleaved-Spectrin α II (D1185) polyclonal antibody（KU）

Swiss-Prot :Q13813

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Fodrin (also named nonerythroid spectrin) is a universally expressed membrane-associated cytoskeletal protein consisting of alpha- and beta-subunits. This protein is important for maintaining normal membrane structure and supporting cell surface protein function. Alpha-fodrin is one of the primary targets cleaved by caspases during apoptosis. The full length 240 kDa protein can be cleaved at several sites within its sequence by activated caspases to yield amino-terminal 150 kDa, carboxy-terminal 120 kDa and 35 kDa major products. Cleavage of alpha-fodrin leads to membrane malfunction and cell shrinkage.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Cleaved-Spectrin α II pAb detects endogenous levels of Cleaved-Spectrin α II protein.

BiowMW :~ 180, 290 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Rho GTPase-activating protein 17; Rho-type GTPase-activating protein 17; RhoGAP interacting with CIP4 homologs protein 1; RICH-1; ARHGAP17; RICH1; MSTP066; MSTP110

Conjugate :Unconjugated

Modification :Cleaved

Western blot (WB) analysis of Cleaved-Spectrin α II (D1185) pAb at 1:500 dilutionLane1:Hela whole cell lysate(40ug)Lane2:A549 whole cell lysate(40ug)Lane3:Panc1 whole cell lysate(40ug)Lane4:PC12 whole cell lysate(40ug)Lane5:CT26 whole cell lysate(40ug)