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TMEM173 polyclonal antibody

货号: BS70551

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS70551

Product Name :TMEM173 polyclonal antibody

Swiss-Prot :Q86WV6

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB IHC IP

Application_all :WB 1:500 - 1:2000 IHC 1:50 - 1:100 IP 1:50 - 1:100

Background :TMEM173, also named as ERIS, MITA, STING and MPYS, is a facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta). TMEM173 mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway. There’re monomer (40 kDa) and dimer (80 kDa) form of TMEM173 in western blot test.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :TMEM173 polyclonal antibody detects endogenous levels of TMEM173 protein.

BiowMW :~ 42 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :STING Signaling,

Alternative Name :Stimulator of interferon genes protein; ERIS; Mediator of IRF3 activation; hMITA; Transmembrane protein 173; TMEM173; ERIS; MITA; STING

Immunogen :Recombinant protein of human TMEM173.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extract of various cells, using TMEM173 antibody.

Immunohistochemistry of paraffin-embedded mouse heart using TMEM173 antibody at dilution of 1:100 (x40 lens).