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IRF9 polyclonal antibody

货号: BS70452

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS70452

Product Name :IRF9 polyclonal antibody

Swiss-Prot :Q00978

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB 1:500 - 1:2000

Background :Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IRF9 polyclonal antibody detects endogenous levels of IRF9 protein.

BiowMW :~ 44 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :RF-9; ISGF3; ISGF3G; p48

Immunogen :Recombinant protein of human IRF9.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of various cell lines, using IRF9 antibody.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）