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Actived-Caspase-7 p20 (D198) polyclonal antibody（KU）

货号: BS7016

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS7016

Product Name :Actived-Caspase-7 p20 (D198) polyclonal antibody（KU）

Swiss-Prot :P55210

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1:500~1:1000

Background :A unique family of Cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, Ced-3/caspase-1, is comprised of caspase-1, caspase-2, caspase-3, caspase-4, caspase-6, caspase-7 (also designated Mch3, ICE-LAP3 or CMH-1), caspase-9 and caspase-10. Ced-3/caspase-1 family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Poly(ADP-ribose) polymerase plays an integral role in surveying for DNA mutations and double strand breaks.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Actived-Caspase-7 p20 polyclonal antibody detects endogenous levels of Actived-Caspase-7 p20 protein.

BiowMW :~ 20 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Regulation of Apoptosis,Inhibition of Apoptosis,

Alternative Name :Caspase-7; CASP-7; Apoptotic protease Mch-3; CMH-1; ICE-like apoptotic protease 3; ICE-LAP3; Caspase-7 subunit p20; Caspase-7 subunit p11; CASP7; MCH3

Immunogen :Synthetic peptide, corresponding Human Actived-Caspase-7 p20.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Actived-Caspase-7 p20 polyclonal antibody at 1:500 dilution Lane1:MCF-7 whole cell lysate(40ug) Lane2:MCF-7 treated with etoposide for 4 hours whole cell lysate(40ug) Lane3:MCF-7 treated with etoposide for 6 hours whole cell lysate(40ug)

The circadian clock gene Bmal1 facilitates cisplatin-induced renal injury and hepatization

JournalCell Death & Disease

ApplicationWB

IF6.304

SpeciesMouse

PMID32522976