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Rel B (S552) polyclonal antibody

货号: BS70007

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS70007

Product Name :Rel B (S552) polyclonal antibody

Swiss-Prot :Q01201

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB

Application_all :WB: 1:500~1:2000

Background :The NFκB transcription factor was originally identified as a protein complex consisting of a DNA-binding subunit and an associated protein. The DNAbinding subunit is functionally related to c-Rel p75 and Rel B p68. The p50 subunit was initially believed to be a functionally unique protein derived from the amino-terminus of a precursor designated p105. A second protein designated p52 (previously referred to as p49) has been identified that can act as an alternative NFκB subunit. Rel B does not bind with high affinity to NFκB sites, but heterodimers between Rel B and p50 bind with an affinity comparable to that of p50 NFκB homodimers. However, Rel B/p50 heterodimers, in contrast to NFκB heterodimers, transactivates transcription of promotors containing κB binding sites.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Rel B (S552) polyclonal antibody detects endogenous levels of Rel B protein.

BiowMW :~ 70 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :NF-kB Signaling,

Alternative Name :Transcription factor RelB; I-Rel; RELB

Immunogen :Synthetic peptide, corresponding to amino acids 530-580 of Human Rel B.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Rel B expression in HepG2 cell lysates,The lane on the left is treated with the antigen-specific peptide.

免疫沉淀（IP）

免疫组织化学（IHC）