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VE-Cadherin polyclonal antibody

货号: BS70004

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS70004

Product Name :VE-Cadherin polyclonal antibody

Swiss-Prot :P33151

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB

Application_all :WB: 1:500~1:2000

Background :The cadherins are a family of Ca 2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy-terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including β-catenin, to regulate cadherin function. VE-cadherin (for vascular endothelial cadherin, also designated cadherin-5) is localized at intercellular junctions of endothelial cells, where it is thought to play a role in the cohesion and organization of intercellular junctions.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :VE-Cadherin polyclonal antibody detects endogenous levels of VE-Cadherin protein.

BiowMW :~ 130 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Adherens Junction signaling,

Alternative Name :Cadherin-5; 7B4 antigen; Vascular endothelial cadherin; VE-cadherin; CD144; CDH5; Cadherin 5

Immunogen :Recombinant full length Human VE-Cadherin.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of VE-Cadherin expression in Jurkat cell lysates,The lane on the left is treated with the antigen-specific peptide.

免疫沉淀（IP）

免疫组织化学（IHC）