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Rock2 polyclonal antibody

货号: BS70002

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS70002

Product Name :Rock2 polyclonal antibody

Swiss-Prot :O75116

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:2000

Background :Rho proteins function as molecular switches that are able to turn cytokinesis on and off. Although little is known about signaling downstream of Rho, a host of putative Rho effector proteins have been de-scribed, including rhophilin, Rhotekin, citron and the serine/threonine kinase, protein kinase N. Two additional Rho-activated serine/threonine kinases have been described, designated Rock-1 and Rock-2 (also referred to as Roka) for Rho-associated coil-containing protein kinase. Rock-1 and Rock-2 share a structural similarity with myotonic dystrophy kinase.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Rock2 polyclonal antibody detects endogenous levels of Rock2 protein.

BiowMW :~ 171 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Regulation of Actin Dynamics,

Alternative Name :Rho-associated protein kinase 2 EC=2.7.11.1 Alternative name(s): Rho kinase 2 Rho-associated, coiled-coil-containing protein kinase 2 Rho-associated, coiled-coil-containing protein kinase II; ROCK-II; p164 ROCK-2; ROCK2; KIAA0619

Immunogen :Recombinant full length Human Rock2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Rock2 polyclonal antibody in extracts from COS7 cells,The lane on the left is treated with the antigen-specific peptide.