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Op18 polyclonal antibody

货号: BS6924

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS6924

Product Name :Op18 polyclonal antibody

Swiss-Prot :P16949

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB IHC IF

Application_all :WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100

Background :Op18 (for oncoprotein 18, also designated stathmin, prosolin or metablastin) is a conserved, tubulin-associated, intracellular phosphoprotein. Many different phosphorylated forms of Op18 are observed, and it is expressed as two different isoforms. Op18 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phosphorylation, for a variety of cell signaling pathways and is involved in both mitosis and differentiation. Op18 is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Op18 polyclonal antibody detects endogenous levels of Op18 protein.

BiowMW :~ 19 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Regulation of Microtubule Dynamics,

Alternative Name :Stathmin; Leukemia-associated phosphoprotein p18; Metablastin; Oncoprotein 18; Op18; Phosphoprotein p19; pp19; Prosolin; Protein Pr22; pp17; STMN1; C1orf215; LAP18; OP18

Immunogen :Recombinant full length Human Op18.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of Jurkat cell lines, using Op18 antibody.

Immunohistochemistry (IHC) analysis of Op18 polyclonal antibody in paraffin-embedded Human Liver tissue.