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TNFRSF14 polyclonal antibody

货号: BS6775

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6775

Product Name :TNFRSF14 polyclonal antibody

Swiss-Prot :Q92956

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1:500~1:2000

Background :HVEM (herpes virus entry mediator A), also known as TR2, ATAR, HVEA, LIGHTR or TNFRSF14 (tumor necrosis factor receptor superfamily, member 14), is a 283 amino acid single-pass type I membrane protein that is widely expressed, with highest expression in lung, spleen and thymus. A member of the TNF receptor superfamily, HVEM mediates the entry of herpes simplex virus (HSV) 1 and 2 into T lymphocytes by serving as an attachment site for the HSV envelope glycoprotein D (gD).HVEM acts as a receptor for two cellular ligands, secreted lymphotoxin and LIGHT. A member of the TNF superfamily produced by activated T-cell, LIGHT is suggested to induce apoptosis and suppress tumor formation. Consisting of three TNFR-Cys repeats, HVEM plays a critical role in HSV pathogenesis. HVEM is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :TNFRSF14 polyclonal antibody detects endogenous levels of TNFRSF14 protein.

BiowMW :~ 31 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Tumor necrosis factor receptor superfamily member 14; Herpes virus entry mediator A; Herpesvirus entry mediator A; HveA; Tumor necrosis factor receptor-like 2; TR2; CD270; TNFRSF14; HVEA; HVEM; UNQ329/PRO509

Immunogen :Recombinant full length Human TNFRSF14.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of HL-60 cell lines, using TNFRSF14 antibody.